During puberty, there is a peak incidence of gynecomastia at approximately what age and Tanner stage?

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Multiple Choice

During puberty, there is a peak incidence of gynecomastia at approximately what age and Tanner stage?

Explanation:
During puberty, gynecomastia occurs because estrogen effects on breast tissue transiently outpace androgen effects as hormones fluctuate. The peak incidence happens in mid-puberty, around age 14, when Tanner stage 3–4 breast development is typical. This is when subareolar glandular tissue most commonly becomes palpable. Most cases are benign and self-limited, often resolving within 6 months to 2 years. If it persists beyond that period or shows concerning features, further evaluation may be warranted.

During puberty, gynecomastia occurs because estrogen effects on breast tissue transiently outpace androgen effects as hormones fluctuate. The peak incidence happens in mid-puberty, around age 14, when Tanner stage 3–4 breast development is typical. This is when subareolar glandular tissue most commonly becomes palpable. Most cases are benign and self-limited, often resolving within 6 months to 2 years. If it persists beyond that period or shows concerning features, further evaluation may be warranted.

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